Xarelto, a blood thinner used to prevent clotting, can cause extreme bleeding. Untreated bleeding elevates Xarelto side effects to a potentially fatal status.




Blood clots

Side Effects

Extreme bleeding

Read more about Xarelto

A photo of a man in a lab, working on creating the AndexXa antidote for Xarelto bleeding.

FDA Delays AndexXa Antidote for Xarelto ...

Ashley Lombardo · January 24, 2018

The AndexXa antidote, intended to stop Xarelto bleeding, awaits FDA approval. The agency will revisit the data in May 2018.

FDA Regulation
A photo of Xarelto pills in a clear disk, representing Xarelto becoming approved for VTE prevention.

Xarelto Gets FDA Approval to Extend VTE ...

Ashley Lombardo · November 17, 2017

The Food and Drug Administration approved the blood thinner Xarelto for extended VTE prevention. The medication has been linked to severe bleeding.

FDA Regulation
Illustration of Elderly Patient Having A Stroke After Study on Xarelto Stroke Prevention Finds It As Effective As Aspirin.

Xarelto Study On Stroke Prevention Ends ...

Ashley Lombardo · October 17, 2017

A Xarelto study on stroke prevention ended early after the drug failed to demonstrate any advantage over taking aspirin.

Research + Findings
An illustration of red blood cells representing Xarelto reversal strategies for bleeding management.

Xarelto Reversal Strategies and Bleeding Management

Ashley Lombardo · October 3, 2017

Xarelto reversal strategies are very important: patients need help with bleeding management in the event of a problem.

A photo of AndexXa, an extreme bleeding reversal agent for Xarelto side effects.

Antidote for Xarelto’s Extreme Bleeding May Be on the Horizon

Ashley Lombardo · February 28, 2017

Portola Pharmaceuticals is manufacturing an antidote for the extreme bleeding side effect linked to Eliquis and Xarelto.

An illustration of scientists and researchers working in a lab.

Did a Defective Blood Machine Alter Xarelto’s Clinical Trial?

Ashley Lombardo · September 30, 2016

A new investigation into Rocket AF, the Xarelto clinical trial, have regulators questioning the safety approval of the popular blood thinner.

Research + Findings