Drug

Zofran

Many of the estimated 85 percent of pregnant women who experience some form of morning sickness will use an anti-nausea medication. 

While some drugs provide relief, others can pose risks in vitro. Zofran birth defects may include cleft lip, craniosynostosis, and congenital malformations. 

Introduced

1991

Treats

Nausea

Side Effects

Birth defects

Read more about Zofran

Photo of baby feet to suggest birth defects in Zofran litigation which are being disputed, despite removal of one supplemental study in October

Birth Defects in Zofran Litigation Disputed, Despite Evidence Removed

James Parker · November 13, 2019

Recent litigation on Zofran has called into question expert testimony, which was removed from the evidence indicating that Zofran causes birth defects when used by pregnant women. Drug manufacturer, GlaxoSmithKline denies that causation of complications beyond heart defects and cleft palate can be proved. Though five cases were removed from the compilation of suits against GSK, the court proceedings wage on -- calling into question whether or not GSK should be required to update their product labeling with an adequate warning.

Legal Developments